Related Experiment Video

Updated: Aug 22, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
14:14

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement

Published on: December 11, 2017

Prevalence of coronary artery disease in patients undergoing valvular operation due to rheumatic involvement

Hüseyin Bozbaş1, Aylin Yildirir, Mehmet Alparslan Küçük

  • 1Department of Cardiology, School of Medicine, Başkent University, Ankara, Turkey. mdhbozbas@yahoo.com

Anadolu Kardiyoloji Dergisi : AKD = the Anatolian Journal of Cardiology
|September 10, 2004
PubMed

Insights

Coronary artery disease (CAD) prevalence in rheumatic heart disease patients undergoing valvular surgery is similar to the general population. Risk factors like diabetes, hypertension, and smoking are more common in rheumatic patients with CAD.

Area of Science:

  • Cardiology
  • Rheumatology
  • Vascular Medicine

Background:

  • Rheumatic heart disease remains a significant global health issue, particularly in developing nations.
  • The relationship between coronary artery disease (CAD) and rheumatic heart disease is not fully understood.
  • Evaluating CAD prevalence in rheumatic heart disease patients is crucial for comprehensive patient management.

Purpose of the Study:

  • To determine the prevalence of coronary artery disease (CAD) in patients undergoing valvular surgery for rheumatic heart disease.
  • To identify atherosclerotic risk factors associated with CAD in this patient cohort.

Main Methods:

  • Retrospective analysis of 346 patients who underwent rheumatic valvular surgery between 1996 and 2002.
  • Coronary angiography was performed in 218 (63%) of the evaluated patients.
  • Comparison of CAD prevalence and risk factors between patients with and without significant coronary artery disease.

Main Results:

  • Coronary artery disease (CAD) was identified in 18.8% (41/218) of patients who underwent angiography.
  • Patients with CAD were significantly older (mean 57.3 vs. 50.5 years) and had higher rates of diabetes mellitus, hypertension, smoking, and family history of CAD.
  • Prevalence of dyslipidemia was similar between groups with and without CAD.

Conclusions:

  • Coronary artery disease prevalence in patients with rheumatic valvular disease is comparable to the age-matched general population.
  • Coronary angiography should be considered in rheumatic heart disease patients with clinical suspicion of CAD or multiple risk factors, especially when invasive valvular assessment is not indicated.
Abstract

More Related Videos

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China08:42

Cox-Maze IV Procedure Concomitant with Valvular Surgery In Situs Inversus Dextrocardia: A Single-Center Experience in China

Published on: February 11, 2022

Related Concept Videos

Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Rheumatic Heart Disease III: Medical Management01:21

Rheumatic Heart Disease III: Medical Management

Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
Rheumatic Heart Disease IV: Nursing Management01:20

Rheumatic Heart Disease IV: Nursing Management

AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...