Related Experiment Video
Updated: Aug 22, 2026

In Vitro Wedge Slice Preparation for Mimicking In Vivo Neuronal Circuit Connectivity
Published on: August 18, 2020
Onset neurones in the anteroventral cochlear nucleus project to the dorsal cochlear nucleus
Robert H Arnott1, Mark N Wallace, Trevor M Shackleton
1MRC Institute of Hearing Research, University Park, Nottingham, NG7 2RD, UK.
Abstract:
Considerable circumstantial evidence suggests that cells in the ventral cochlear nucleus, that respond predominantly to the onset of pure tone bursts, have a stellate morphology and project, among other places, to the dorsal cochlear nucleus. The characteristics of such cells make them leading candidates for providing the so-called "wideband inhibitory input" which is an essential part of the processing machinery of the dorsal cochlear nucleus. Here we use juxtacellular labeling with biocytin to demonstrate directly that large stellate cells, with onset responses, terminate profusely in the dorsal cochlear nucleus. They also provide widespread local innervation of the anteroventral cochlear nucleus and a small innervation of the posteroventral cochlear nucleus. In addition, some onset cells project to the contralateral dorsal cochlear nucleus.
Related Concept Videos
Auditory Pathway
When viewed cross-sectionally, the cochlea reveals the scala vestibuli and scala tympani flanking the...
The Cochlea
Diencephalon: Thalamus and Information Relay
Spinal Cord: Information Processing
Sensory Information Processing
Sensory information processing begins at the sensory receptors located in the skin and other tissues, which detect somatic sensory stimuli such as touch, temperature, or pain. These receptors function as catalysts, initiating...
Hair Cells
Functions of the Nervous System

