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[Insight into surface structure and hemocompatibility of fluorinated poly(ether urethane)s and poly(ether urethane)s
Hong Tan1, Jiehua Li, Xingyi Xie
1State Key Laboratory of Polymer Materials Engineering, College of Polymer Science and Engineering, Sichuan University, Chengdu 610065, China.
Summary
Fluorinated polyurethanes enhance surface properties and hemocompatibility in polymer blends. Even low concentrations improve fluorine concentration, reducing platelet adhesion for better biocompatibility.
Area of Science:
- Polymer Science
- Materials Science
- Biomaterials
Context:
- Fluorinated polyurethanes possess desirable properties like low surface energy and biocompatibility.
- These characteristics make them attractive for various applications.
- Understanding their behavior in blends is crucial for material development.
Purpose:
- Investigate the impact of varying fluorinated polyurethane concentrations on blend surface structure.
- Evaluate the hemocompatibility of these polyurethane blends.
- Correlate surface properties with hemocompatibility and fluorine content.
Summary:
- Surface analysis (XPS, AFM, contact angle) revealed high fluorine concentration on blend surfaces, even at low fluorinated polyurethane content.
- All tested blends and fluorinated poly(ether urethane)s demonstrated good hemocompatibility, outperforming standard poly(ether urethane)s.
- Platelet adhesion was suppressed due to increased hydrophobicity and low surface tension, linked to CF3 group concentration.
Impact:
- The study highlights that high surface hydrophobicity in polyurethane blends is independent of fluorinated polyurethane content but dependent on CF3 group concentration.
- Findings suggest potential for developing advanced biomaterials with enhanced hemocompatibility.
- Optimized fluorinated polyurethane blends can offer improved performance in biomedical applications.