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Updated: Aug 22, 2026

Microinjection-based System for In Vivo Implantation of Embryonic Cardiomyocytes in the Avian Embryo
Published on: February 17, 2019
Cardiovascular embryology
R Abdulla1, G A Blew, M J Holterman
1Pediatric Cardiology, The University of Chicago. MC4051, 5841 S. Maryland Ave., Chicago, IL 60637-1470, USA. rabdulla@peds.bsd.uchicago.edu
Abstract:
During the first 20 days of development, the human embryo has no cardiovascular structure. Over the next month, the heart and great vessels complete their development and look very much like they will at full gestation. This amazing process transforms isolated angiogenic cell islets into a complex, four-chambered structure. During this transformation, the single heart tube begins to beat at 23 days of development and by 30 days blood circulates through the embryo.
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