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Pandoraea bacteremia in a cystic fibrosis patient with associated systemic illness

Lindsey N Johnson1, Jin-Young Han, Samuel M Moskowitz

  • 1Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA.

The Pediatric Infectious Disease Journal
|September 14, 2004
PubMed

Insights

Pandoraea bacteria, often found in cystic fibrosis (CF) patients, can cause bloodstream infections (bacteremia) and illness. This case suggests Pandoraea may be a significant pathogen in immunocompromised individuals.

Area of Science:

  • Microbiology
  • Infectious Diseases
  • Clinical Medicine

Background:

  • Pandoraea is a recently identified bacterial genus.
  • This genus is frequently isolated from the sputum of cystic fibrosis (CF) patients.
  • The pathogenic potential of Pandoraea remains largely unknown.

Observation:

  • A case of Pandoraea bacteremia is described in a 16-year-old patient with cystic fibrosis.
  • The patient presented with associated clinical disease.

Findings:

  • This case demonstrates Pandoraea bacteremia in a cystic fibrosis patient.
  • The infection was linked to the development of clinical illness.

Implications:

  • Pandoraea should be recognized as a potential pathogen in susceptible individuals, particularly those with cystic fibrosis.
  • Further research is warranted to understand the pathogenicity and clinical significance of Pandoraea infections.

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