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The effect of the presence of muscle tissue in a bone healing site
Andy Petroianu1, Renato Abranches Corsetti, Luiz Ronaldo Alberti
1Department of Surgery, Medical School, Federal University of Minas Gerais, Belo Horizonte, MG, Brazil. petroian@medicina.ufmg.br
Purpose:
The recovery of a bone fracture is a process that is not yet fully understood. The literature conflicts on the results obtained by the interposition of foreign tissue inside a damaged bone. The objective of the present study was to ascertain the effect of placing muscle tissue between the stumps of a fractured bone.
Method:
The study was carried out on 10 rabbits divided into 2 groups (n = 5): Group 1--partial fracture of the humerus and interposition of muscle tissue; Group 2--complete fracture of the humerus and interposition of muscle tissue. The fractured limb of all animals was immobilized for 8 weeks. At the end of this time, the rabbits were killed and their operated humeri were carefully removed for roentgenological and histological assessment.
Results:
All humeri of Group 1 recovered their integrity and normal aspect. However, the healing of the humeri of Group 2 was not perfect. Gross angulation of the bone diaphysis occurred in all animals, and immature trabecular bone, osteochondral tissue, and persistence of muscle tissue substituted normal bone.
Conclusions:
Interposed muscle does not affect partial bone fracture healing but causes instability in a complete fracture.
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