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Pharmacoeconomic burden of undertreating hypertension
Luca Degli Esposti1, Giorgia Valpiani
1CliCon Srl, Health, Economics & Outcome Research, Ravenna, Italy. luca.degliesposti@clicon.it
Insights
Undertreating hypertension leads to significant cardiovascular events and costs. More research is needed to quantify the economic and clinical impact of undertreatment and improve hypertension management.
Area of Science:
- Pharmacoeconomics
- Cardiovascular Medicine
- Public Health
Background:
- Antihypertensive drug therapy is crucial for reducing cardiovascular morbidity and mortality.
- However, approximately 50% of hypertensive patients are undertreated or inadequately controlled.
- Undertreatment of hypertension significantly impacts drug therapy effectiveness and cost-effectiveness.
Purpose of the Study:
- To review the pharmacoeconomic burden of undertreating hypertension.
- To identify key issues, measure undertreatment extent and associated costs.
- To discuss essential aspects of hypertension disease management.
Main Methods:
- Literature review focusing on pharmacoeconomic burden and undertreatment of hypertension.
- Analysis of clinical and economic consequences of uncontrolled blood pressure.
- Discussion of disease management strategies for hypertension.
Main Results:
- The pharmacoeconomic burden of undertreating hypertension is substantial but under-researched.
- Lack of epidemiological studies in clinical practice limits data availability.
- Current data suggests significant clinical and economic losses due to inadequate hypertension control.
Conclusions:
- Undertreatment of hypertension poses a major pharmacoeconomic challenge.
- There is a critical need for more research, including appropriateness and cost-effectiveness studies.
- Improved hypertension management is essential to mitigate clinical and economic consequences.
Abstract:
Many studies have shown the importance of antihypertensive drug therapy as a factor in reducing the risk of cardiovascular morbidity and mortality, and in containing the cost of managing hypertension and its complications. Nevertheless, the evidence in clinical practice indicates about half of hypertensive patients do not receive pharmacological treatment and about half of treated patients do not achieve blood pressure level control. Undertreating hypertension is the leading cause of failure in drug therapy effectiveness and cost effectiveness. The pharmacoeconomic burden of undertreating hypertension can be defined as the clinical (number of cardiovascular events) and economic (costs of managing cardiovascular events) consequences that would have been avoided by adequate control of blood pressure levels. In the last few years, the increase in this burden and the restriction of budget constraints has raised the awareness of healthcare providers with regards to the need to achieve better performance and to improve disease management of hypertension. This review aims to present the current situation regarding the pharmacoeconomic burden of undertreating hypertension by identifying the key issues of this medical condition, defining and measuring the extent of undertreatment, defining and measuring costs associated with undertreatment, and discussing some fundamental aspects of disease management for hypertension. The pharmacoeconomic burden of undertreating hypertension appears to be an extremely important phenomenon for which there is currently only very limited adequate research. The present dearth of appropriate data can be largely attributed to the lack of epidemiological studies in clinical practice. Future studies are necessary for a more precise quantification of the therapeutic and economic impact of undertreating arterial hypertension in clinical practice (appropriateness studies) and for more precise selection of antihypertensive drugs on the basis of the different cost-effectiveness profiles detected in 'real world' settings (cost-effectiveness studies).
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