Related Experiment Video
Updated: Feb 1, 2026

Author Spotlight: Exploring the Relationship Between Lipotoxicity and HFpEF
Published on: February 23, 2024
Food and nutrient intake in relation to mental wellbeing
Reeta Hakkarainen1, Timo Partonen, Jari Haukka
1Department of Mental Health and Alcohol Research, National Public Health Institute, Helsinki, Finland. reeta.hakkarainen@ktl.fi
Background:
We studied food consumption and nutrient intake in subjects with depressed mood, anxiety and insomnia as indices of compromised mental wellbeing.
Methods:
The study population consisted of 29,133 male smokers aged 50 to 69 years who entered the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study in 1985-1988. This was a placebo-controlled trial to test whether supplementation with alpha-tocopherol or beta-carotene prevents lung cancer. At baseline 27,111 men completed a diet history questionnaire from which food and alcohol consumption and nutrient intake were calculated. The questionnaire on background and medical history included three symptoms on mental wellbeing, anxiety, depression and insomnia experienced in the past four months.
Results:
Energy intake was higher in men who reported anxiety or depressed mood, and those reporting any such symptoms consumed more alcohol. Subjects reporting anxiety or depressed mood had higher intake of omega-3 fatty acids and omega-6 fatty acids.
Conclusions:
Our findings conflict with the previous reports of beneficial effects of omega-3 fatty acids on mood.
Related Concept Videos
Regulation of Food Intake
Traits, Mood, and Subjective Wellbeing
Neuroticism and...
Absorption of Nutrients
Enterocytes, which are specialized polar epithelial cells, line the mucosa of the small intestinal walls. These cells...
Regulation of Water Intake
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Higher Mental Functions of the Brain: Language
Language formation and comprehension take place in the dominant hemisphere. The dominant hemisphere is responsible for understanding the meaning of spoken, written, or sign language, as well as the ability to communicate. For most people, the left hemisphere is the dominant one. The right hemisphere, then, gives tone and emotional context to the...

