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Updated: Aug 22, 2026
A Novel Use of Three-dimensional High-frequency Ultrasonography for Early Pregnancy Characterization in the Mouse
Published on: October 24, 2017
Three-dimensional first trimester fetal volumetry: comparison with crown rump length
R Aviram1, D Kamar Shpan, O Markovitch
1Ultrasound Unit, Deparment of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba 44281, Israel. Bensonm@clalit.org.il
Background:
Ultrasonographic volumetry measurements of human fetus have become possible using three-dimensional ultrasound systems.
Objective:
To evaluate the weekly increase of fetal volume during the first trimester of normal pregnancies compared to the crown rump length and creating a first trimester fetal volume nomogram.
Methods:
Crown rump length and three-dimensional ultrasonographic volumetry measurements performed on 72 first trimester fetuses using virtual organ computer aided analysis (VOCAL).
Results:
A significant direct correlation (r = 0.939) was found between the calculated fetal volumes and crown rump lengths. A 6-12 weeks gestation fetal volume nomogram was proposed.
Conclusion:
Fetal volume database in the first trimester may serve as a reference table for diagnosis of early pregnancy failure.
