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Updated: Aug 22, 2026
Modeling Dysplastic and Functional Lung Alveolar Repair after Influenza Infection
Published on: September 19, 2025
Influenza A pneumonia presenting as progressive focal infiltrates in a stem cell transplant recipient
John D Scott1, Janet A Englund, David Myerson
1Department of Medicine, University of Washington, Harborview Medical Center, 325 Ninth Avenue, Box 359938, Seattle, WA 98104-2499, USA. jdscott@u.washington.edu
Background:
Stem cell transplant recipients are susceptible to pulmonary infections, including influenza A. Typically, isolated influenza pneumonia has a diffuse, interstitial infiltrate pattern.
Objectives:
To describe the unusual clinical and radiographic course of influenza A pneumonia in a stem cell transplant recipient.
Study Design:
Case report in which microbiologic assays, bronchoscopic and pathologic specimens are obtained.
Results:
We describe a patient with influenza A pneumonia 8 months following a peripheral blood stem cell transplant who presented with minimal respiratory symptoms and rapidly progressing, focal pulmonary infiltrates. The large size and appearance of the masses have not been reported before in a patient with isolated influenza.
Conclusion:
This case highlights the differences of presentation and importance of early diagnosis and treatment of immunocompromised patients infected with influenza.
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Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...