A transcranial magnetic stimulation study of the ipsilateral silent period in lower limb muscles

The lower limb ipsilateral silent periods (ISP) were determined with transcranial magnetic stimulation in 30 normal subjects using a round coil. The mean duration and transcallosal conduction time were comparable to values obtained from upper limb recordings. No age-related correlation was found for either parameter, corroborating previous imaging and pathological studies of interhemispheric pathways. Our results highlight the feasibilty of eliciting ISPs in the lower limbs, relevant for future studies of interhemispheric interaction in clinical and research settings.