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Multicenter validation of the cppB gene as a PCR target for detection of Neisseria gonorrhoeae
S M Bruisten1, G T Noordhoek, A J C van den Brule
1GG&GD Municipal Health Service, Public Health Laboratory, Nieuwe Achtergracht 100, 1018 WT Amsterdam, The Netherlands. sbruisten@gggd.amsterdam.nl
Journal of Clinical Microbiology
|September 15, 2004
Abstract:
The cppB gene is often used as a target for detection of Neisseria gonorrhoeae by PCR. Using a coded panel of 500 DNA samples, we determined that the cppB gene is missing in 5.8% of N. gonorrhoeae strains, and therefore we consider the cppB gene to be an unsuitable target.
