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Sensory neuropathy in vasculitis: a clinical, pathologic, and electrophysiologic study
J-H Seo1, H F Ryan, G C Claussen
1Department of Rehabilitation Medicine, School of Medicine, Chonbuk National University, Chonju, Republic of Korea.
Background:
Vasculitis is not usually considered as a cause of symmetric sensory neuropathy.
Objective And Methods:
To present the clinical, pathologic, and electrophysiologic features of 17 (16%) cases of sensory neuropathy in vasculitis (SNV) among 106 cases with histologically proven vasculitic neuropathy that were collected over the last 30 years.
Results:
In 41% of cases, SNV was found as systemic vasculitic neuropathy in association with primary vasculitic disease. The most common clinical presentation was symmetric polyneuropathy, seen in 53% of cases. The most common nerve conduction pattern was diffuse neuropathy pattern of axonal degeneration. Sural nerve biopsy was diagnostic in 88% of cases. In two cases, muscle biopsy was necessary for the definite diagnosis of vasculitis. Non-systemic SNV is usually benign. Of 11 patients followed for longer than 2 years, none developed motor weakness due to neuropathy.
Conclusion:
Sensory neuropathy, regardless of symmetry, can be due to vasculitis.
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