Disseminated intravascular coagulation. Principles, treatment, nursing management

Disseminated intravascular coagulation is an abnormal syndrome that occurs secondary to clinical conditions that result in widespread microthrombosis, macrothrombosis, and hemorrhage. Depending on the primary clinical condition and the intensity and duration of the bleeding episode, mortality can be high. Treatment is first directed at the primary clinical condition followed by measures to stabilize coagulation and fibrinolysis and to replenish body fluids, blood, and blood products. Continual assessment of clinical manifestations and evaluation of laboratory values are used to monitor therapy effectiveness.