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Detection of MicroRNA Expression in the Kidneys of Immunoglobulin A Nephropathic Mice
Published on: July 8, 2020
Histopathological atlas of renal diseases--IgA nephropathy
Franco Ferrario1, Maria Pia Rastaldi
1Renal Immunopathology Center, S. Carlo Borromeo Hospital and Nuova Nefrologia Research Association, Milan, Italy.
Abstract:
The characteristic and diagnostic lesion of idiopathic IgA nephropathy (IgAN, Berger's disease) is glomerular IgA deposition, as a unique or predominant positive immunoglobulin. Despite the relatively uniform feature of the immunohistological pattern, the morphological lesions observed by light microscopy are extremely variable. This variability in glomerular and interstitial alterations has frequently created some difficulties in histological classification.
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