Related Experiment Video
Updated: Aug 22, 2026

Assessment of Nerve Injury-Induced Mechanical Hypersensitivity in Rats Using an Orofacial Operant Pain Assay
Published on: July 26, 2022
Mandibular endodontic-related paresthesia
George J Vasilakis1, Callie M Vasilakis
1University of Medicine and Dentistry of New Jersey, Newark, USA.
Abstract:
A 57-year-old woman sought treatment for mandibular swelling (of two weeks duration), pain, and paresthesia in the region of the left canine and first premolar. The teeth had undergone endodontic therapy; in addition, they partially supported a long-span fixed partial denture. The patient was concerned about the possibility of a serious neoplastic condition. The initial panoramic radiograph demonstrated a large periapical pathology area associated with the first premolar. Eventually, both the canine and first premolar teeth were retreated, although the paresthesia did not resolve for approximately four months. A brief review of endodontic-associated paresthesia is provided, along with a description of the therapy and postoperative radiographs taken 20 months later.
Related Concept Videos
Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or grinding food.
Blood and Nerve Supply to the Bones
Nutrient Artery
The nutrient artery is the main blood vessel that enters the diaphysis via the nutrient foramen. While most long bones have only one nutrient foramen, large bones, such as the femur, may have two. This...
