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Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
10:03

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty

Published on: January 28, 2020

Relationship between peripheral leukocyte count and the severity of stable angina determined by coronary angiography

Seung Ha Park1, Jeung Mook Kang, Bum Soo Kim

  • 1Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

The Korean Journal of Internal Medicine
|September 16, 2004
PubMed

Insights

Increased peripheral leukocyte count predicts stable angina progression, not its cause. This finding aids in identifying high-risk patients for intervention.

Area of Science:

  • Cardiology
  • Inflammation Research
  • Vascular Biology

Background:

  • Inflammation is a known risk factor for cardiovascular disease (CVD).
  • The link between peripheral leukocyte count and stable angina severity requires further investigation.
  • This study examines peripheral leukocyte count in relation to stable angina severity.

Purpose of the Study:

  • To clarify the relationship between peripheral leukocyte count and stable angina severity.
  • To evaluate peripheral leukocyte count as a risk factor for stable angina.
  • To analyze the correlation between leukocyte count and angina severity using Gensini's score.

Main Methods:

  • Retrospective review of 108 stable angina patients and 92 controls.
  • Analysis of peripheral leukocyte count as a risk factor.
  • Correlation analysis between leukocyte count and Gensini's score in angina patients.

Main Results:

  • Stable angina patients had higher age, hypertension, diabetes, fasting blood sugar, and lower HDL than controls.
  • Diabetes and older age were independent risk factors for stable angina.
  • A positive correlation was found between peripheral leukocyte count and Gensini's score (p=0.015).

Conclusions:

  • Elevated peripheral leukocyte count may predict stable angina progression rather than being a direct cause.
  • This correlation can help identify high-risk patients needing proactive interventional therapy.
Abstract

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