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Updated: Aug 22, 2026

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
Published on: August 16, 2016
Polymer translocation through a nanopore induced by adsorption: Monte Carlo simulation of a coarse-grained model
Andrey Milchev1, Kurt Binder, Aniket Bhattacharya
1Institut für Physik, Johannes-Gutenberg-Universität Mainz, Staudinger Weg 7, 55099 Mainz, Germany.
Abstract:
Dynamic Monte Carlo simulation of a bead-spring model of flexible macromolecules threading through a very narrow pore in a very thin rigid membrane are presented, assuming at the cis side of the membrane a purely repulsive monomer-wall interaction, while the trans side is attractive. Two choices of monomer-wall attraction epsilon are considered, one choice is slightly below and the other slightly above the "mushroom to pancake" adsorption threshold epsilon(c) for an infinitely long chain. Studying chain lengths N=32, 64, 128, and 256 and varying the number of monomers N(trans) (time t=0) that have already passed the pore when the simulation started, over a wide range, we find for epsilon
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