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Updated: Aug 22, 2026
Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
Published on: October 10, 2016
Biocompatibility and antibacterial activity studies of polyamidoamine (PAMAM) dendron, side chain dendritic
Samaresh Ghosh1, Ajit K Banthia
1Materials Science Centre, Indian Institute of Technology, Kharagpur, 721302, India.
Abstract:
Cytotoxicity of both polyamidoamine dendritic diol (PAMAM) and side chain dendritic oligourethane (SCDOU) was studied through interaction with mammalian fibroblast cells (L929). Cell metabolic activity in the presence of dendritic polymers was measured using an MTT assay exhibiting significant cell viability. Additionally, the antibacterial activity of PAMAM dendron, SCDOU, as well as their silver-doped structures was studied against Escherichia coli bacteria. The results showed that the silver-doped structures attain high antibacterial activity. Formation of silver-doped dendritic polymers was investigated from the UV-visible plasmon absorption band of silver particles.
