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Eosinophilic cystitis induced by penicillin.

Anna Tsakiri1, Ingegerd Balslev, Peter Klarskov

  • 1Section of Urology, Glostrup Hospital, University of Copenhagen, Denmark. pzivlaei@bksv.com

International Urology and Nephrology
|September 17, 2004
PubMed
Summary

Penicillin treatment for abdominal actinomycosis can cause painful bladder disease and eosinophilic cystitis. These adverse effects resolved after discontinuing the penicillin medication.

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Area of Science:

  • Urology
  • Pharmacology
  • Infectious Diseases

Background:

  • Abdominal actinomycosis is a rare bacterial infection often treated with penicillin.
  • Adverse drug reactions can manifest in various organ systems.
  • Eosinophilic cystitis is an uncommon bladder inflammation.

Observation:

  • A 30-year-old female patient presented with symptoms indicative of painful bladder syndrome.
  • The patient was undergoing treatment with penicillin for abdominal actinomycosis.
  • Diagnostic evaluation revealed eosinophilic cystitis.

Findings:

  • Eosinophilic cystitis and painful bladder disease were identified as adverse effects of penicillin therapy.
  • Cessation of penicillin led to the complete resolution of the patient's urological symptoms.

Implications:

  • This case highlights a potential, albeit rare, adverse effect of penicillin.
  • Clinicians should consider drug-induced cystitis in patients presenting with unexplained bladder pain during antibiotic treatment.
  • Awareness of this association may improve diagnosis and patient management for similar cases.

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