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Updated: Aug 22, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
Published on: April 12, 2017
[Advances in diagnosis and treatment of renal cell carcinoma]
Bernard Debré1, Michaël Peyromaure, Djillali Saïghi
1Service d'urologie, Hôpital Cochin, 27 rue du faubourg Saint-Jacques, 75014 Paris.
Abstract:
Over the last two decades, several improvements have been made in the diagnosis and treatment of renal carcinoma. In the past, renal cancer was usually discovered after hematuria, pain, or palpation of a lumbar mass, and required total nephrectomy. Today, about 40% of renal tumors are discovered incidentally by ultrasonography or computed tomography. Therefore, the majority of renal carcinomas are discovered at an early stage. Partial nephrectomy has been developed for polar and small tumors. This surgery can now be performed using a laparoscopic approach, thereby decreasing morbidity and shortening the hospital stay.
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