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A Suction Blister Protocol to Study Human T-cell Recall Responses In Vivo
Published on: August 11, 2018
[Tuberculin test: proposal for a pre-test risk assessment questionnaire and a standardized evaluation]
V Di Gaetano1, S Corrao, C Mammina
1Scuola di Specializzazione in Igiene e Medicina Preventiva, Università degli Studi di Palermo.
Abstract:
Relevance of latent infection in the epidemiology of tuberculosis (TB) is expected to increase in many developed countries. Indeed, many demographic, social and public health changes could contribute to the expansion of groups or communities at significantly higher risk than the general population for infection to Mycobacterium tuberculosis or progression from latent to active disease. Tuberculin skin testing (TB), the gold standard for diagnosis of M. tuberculosis infection, is imperfect and prone to false positive and negative results, unless strictly targeted and carefully standardized for reliable performance and interpretation. This paper proposes a pre-test risk assessment questionnaire and standardized criteria for evaluation of TB test according to international guidelines.
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