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Breast-feeding and risk of hospitalization for all causes and fever of unknown origin
Rosa Pardo-Crespo1, Rocio Pérez-Iglesias, Javier Llorca
1Division of Paediatrics, University of Cantabria School of Medicine, Santander, Spain.
Insights
Exclusive breastfeeding may reduce hospitalizations in infants. This study found shorter breastfeeding duration in hospitalized children, particularly those under six months, for all admission causes and fever of unknown origin (FUO).
Area of Science:
- Pediatrics
- Public Health
- Epidemiology
Background:
- Breastfeeding is associated with reduced risk of respiratory and gastrointestinal infections in children under two.
- The study investigated the link between breastfeeding and hospital admissions for all causes and fever of unknown origin (FUO).
Purpose of the Study:
- To analyze the association between breastfeeding duration and hospital admissions in children under 24 months.
- To identify factors influencing breastfeeding practices and their impact on child hospitalization.
Main Methods:
- A case-reference study was conducted in Cantabria, Spain, involving 336 hospitalized children and a matched control group.
- Data on breastfeeding, socioeconomic status, and employment were collected. Adjusted odds ratios (ORs) and mean breastfeeding duration were calculated.
Main Results:
- Breastfeeding frequency was lower in hospitalized children (75.6%) compared to controls (82.3%).
- Univariate analysis showed a negative trend between breastfeeding length and hospital admissions for all causes and FUO.
- Adjusted mean breastfeeding duration was significantly shorter in hospitalized infants under six months for all admission causes and FUO.
Conclusions:
- Hospitalized children, especially those under six months, had a shorter duration of breastfeeding.
- These findings highlight the importance of breastfeeding for preventing hospitalizations, even after adjusting for confounding factors.
Background:
Breast-feeding has shown to give a reduction in the risk of hospitalization due to respiratory tract infections and gastrointestinal conditions during the first two years of life. The association of breast-feeding with all admission causes and with fever of unknown origin (FUO) was analysed.
Methods:
A case-reference study in Cantabria (northern Spain) was carried out. Cases (n=336) were hospitalized children aged less than 24 months at University of Cantabria Hospital; the reference was a 1:1 matched (by time from delivery to admission) sample of children from mothers delivering at the same hospital. Information on breast-feeding, socioeconomic variables and employment were obtained. Odds ratios (ORs), their 95% confidence intervals (CIs), and mean length of breast-feeding were estimated after adjusment for confounding variables.
Results:
In the reference population, shorter duration of breast-feeding was associated with smoking, lower educational level, and less privileged social strata. The frequency of breast-feeding was higher in the reference than in the cases, 82.3% vs 75.6% (p=0.023). Significant negative trends were noted in univariate analyses between the length of breast-feeding and both all admission causes and FUO, although the statistical significance was lost after adjusting for confounding variables (educational level, social class, smoking, and use of incubator after delivery). The adjusted mean length of breast-feeding was shorter in hospitalized children < or = 6 months old for both all admission causes (40.6 +/- 5.4 vs 99.5 +/- 5.4, p < 0.001) and FUO (40.8 +/- 12.4 vs 91.7 +/- 12.4, p=0.006).
Conclusion:
Breast-feeding time is shorter in hospitalized children for both all admission causes and FUO.
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