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Pharmacotherapies for problematic psychostimulant use: a review of current research
James Shearer1, Linda R Gowing
1National Drug and Alcohol Research Centre, University of New South Wales, Sydney, Australia. j.shearer@unsw.edu.au
Abstract:
This review summarizes the current status of clinical research on pharmacotherapies for problematic psychostimulant use. The use of psychostimulants, including amphetamine, cocaine and ecstasy, is increasingly a feature of Australian life as is the presentation of patients with psychostimulant disorders. A lack of experience, resources and treatment options have constrained the response of treatment services to such problems. Despite extensive research, particularly in the area of cocaine, no pharmacotherapy has been proven effective in the management of psychostimulant disorders. The harms associated with problematic psychostimulant use warrant further controlled research in innovative approaches integrated with psychosocial interventions.
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Cocaine can be administered via snorting, injection, or smoking. It primarily functions by blocking the reuptake of dopamine, resulting in a euphoric high characterized by an intense sensation of happiness and...