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Updated: Jul 21, 2026

Pre-clinical Evaluation of Tyrosine Kinase Inhibitors for Treatment of Acute Leukemia
Published on: September 18, 2013
Natural killer lymphoma/leukemia: an uncommon pediatric case with indolent course
Andrea Di Cataldo1, Gregoria Bertuna, Elena Mirabile
1Centre of Paediatric Haematology and Oncology, University of Catania, Via Santa Sofia, 78, 95123 Catania, Italy. adicata@unict.it
Abstract:
Natural killer (NK) cell lymphomas are rare in the USA and Europe but more common in Asia and Central America although very rare among children. We report a case of Epstein-Barr virus-positive NK lymphoma/leukemia, that showed peculiar features represented by a very long clinical course with a significant interval between the first clinical signs and the diagnosis, detection of neoplastic cells in the peripheral blood but not in the bone marrow, and good response to treatment and clinical outcome.
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