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On the difference between reference radiations used in radiobiology.

J Chen1

  • 1Radiation Protection Bureau, Health Canada 6302D1, 775 Brookfield Road, Ottawa K1A 1C1, Canada. jing_chen@hc-sc.gc.ca

International Journal of Radiation Biology
|September 17, 2004
PubMed
Summary

Hard gamma-rays from Cobalt-60 or Cesium-137 are ideal reference radiations. Microdosimetric analysis supports their use for specifying relative biological effectiveness in radiation protection.

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Area of Science:

  • Radiological Physics
  • Radiation Dosimetry
  • Biophysics

Background:

  • The International Commission on Radiological Protection (ICRP) recommends hard gamma-rays as common reference radiation.
  • ICRP Publication 92 highlights the need for standardized radiation sources in radiological protection.

Purpose of the Study:

  • To provide microdosimetric evidence supporting the use of Cobalt-60 (⁶⁰Co) or Cesium-137 (¹³⁷Cs) gamma-rays as common reference radiation.
  • To evaluate the suitability of these gamma-rays for specifying relative biological effectiveness (RBE).

Main Methods:

  • Microdosimetric properties of seven common reference radiations were analyzed.
  • The proximity function, derived from Monte Carlo simulations of energy deposition, was used to quantify differences in radiation quality.

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Main Results:

  • Significant differences in microdosimetric properties were observed among the seven reference radiations.
  • However, hard gamma-rays (⁶⁰Co, ¹³⁷Cs) showed no significant differences in energy deposition spectra across relevant biological distances.

Conclusions:

  • Microdosimetric data confirm that gamma-rays from ⁶⁰Co or ¹³⁷Cs are the most appropriate reference radiations.
  • These findings support their designation for the specification of RBE in radiation protection applications.