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Related Experiment Videos

ABO-incompatible kidney transplantation.

Mark D Stegall1, Patrick G Dean, James M Gloor

  • 1Department of Surgery, Division of Transplantation Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA. stegall.mark@mayo.edu

Transplantation
|September 17, 2004
PubMed
Summary
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ABO incompatible kidney donation is now a viable option. Advances in paired kidney exchange and desensitization protocols offer alternatives to waiting for a deceased donor kidney transplant.

Area of Science:

  • Nephrology
  • Transplantation Immunology

Background:

  • ABO incompatible donors are a barrier to living donor kidney transplantation.
  • Paired kidney donor exchange and desensitization protocols are emerging solutions.

Purpose of the Study:

  • To review therapeutic options for ABO incompatible living donor kidney transplantation.
  • To emphasize the rationale and outcomes of ABO incompatible kidney transplants.

Main Methods:

  • Review of current literature on ABO incompatible kidney transplantation.
  • Analysis of paired kidney exchange programs and desensitization protocols.

Main Results:

  • Successful implementation of paired kidney exchange programs.
  • Development of effective protocols to overcome ABO blood group barriers.

Related Experiment Videos

  • Improved outcomes for ABO incompatible living donor kidney transplantation.

    • Conclusions:

    • ABO incompatible living donor kidney transplantation is a feasible and increasingly successful option.
    • These advancements offer alternatives to deceased donor waiting lists for many patients.