Related Experiment Video
Updated: Aug 19, 2026

Induction of Experimental Autoimmune Hypophysitis in SJL Mice
Published on: December 17, 2010
Abstract:
I have described some of the currently known characteristics of a group of pituitary adenomas that produce no syndrome of hormone secretion. These tumors, termed endocrine-inactive, are engaged in low levels of endocrine activity and under certain circumstances can secrete hormones, primarily glycoprotein hormones and their subunits. I have advocated a more vigorous attempt to achieve total removal of these usually large tumors because of my conviction that many, although certainly not all, can be removed completely with preservation of anterior pituitary function and, possibly, recovery of lost anterior pituitary function. Transsphenoidal removal of endocrine-inactive tumors is safe as well as effective and, in the foreseeable future, will continue to be the treatment of first choice.
Related Concept Videos
The Pituitary Gland
Hormones of the Pituitary Gland
The most abundantly secreted hormone from the anterior lobe is the growth hormone, which controls overall growth by...
The Parathyroid Glands
Oxyphil cells, whose functions remain elusive, emerge during late puberty, adding a layer of complexity to the parathyroid gland's intricacies. In contrast, principal parathyroid cells undertake a vital role by producing...
Major Hormones and Their Functions
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and lactation.
Hypothyroidism II: Pathophysiology
Cushing Syndrome II: Pathophysiology

