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AnoXcel: an Anopheles gambiae protein database.
J M C Ribeiro1, P Topalis, C Louis
1Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892-0425, USA. jribeiro@niaid.nih.gov
Insect Molecular Biology
|September 18, 2004
Summary
Anopheles gambiae proteome data is now available in an organized, searchable spreadsheet format on AnoBase. This resource aids scientists in annotating mosquito proteome subsets from various experimental data types.
Area of Science:
- Proteomics
- Bioinformatics
- Mosquito Biology
Background:
- The Anopheles gambiae mosquito is a vector for malaria.
- Understanding its proteome is crucial for developing control strategies.
Purpose of the Study:
- To organize and present the Anopheles gambiae proteome in a user-friendly format.
- To facilitate the annotation of proteome subsets for researchers.
Main Methods:
- A hyperlinked spreadsheet was created to house proteomic data.
- Information included signal peptides, transmembrane domains, database similarities, and chromosomal locations.
- The data is hosted on AnoBase and accessible via a dedicated web portal.
Main Results:
- The Anopheles gambiae proteome is systematically organized.
- Data is downloadable and searchable for specific research needs.
- The resource supports the analysis of transcriptomic, microarray, and mass spectrometry data.
Conclusions:
- The AnoBase resource provides a valuable tool for Anopheles gambiae proteome research.
- Streamlined data access enhances the efficiency of proteomic subset annotation.
- This organization aids in understanding mosquito biology and malaria transmission.