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Updated: Aug 22, 2026

An Integrated Approach for Microprotein Identification and Sequence Analysis
Published on: July 12, 2022
MOP-UP: an online tool for finding strain-specific primers or motifs in DNA or protein alignments
1Central Public Health Laboratory, Genomics, Proteomics and Bioinformatics Unit, London, UK. anthony.underwood@hpa.org.uk
Abstract:
MOP-UP is a web-based application that enables efficient searching of nucleic acid or amino-acid alignments for sequences or motifs that are unique to a subset of the members represented in the alignment. This has applications in the design of assays that aim to detect particular strains or species. Since molecular-based characterisation of microbes is becoming increasingly important, MOP-UP can aid microbiologists in finding the best loci on which to base such assays. The program is accessible at: http://www.hpa.org.uk/srmd/bioinformatics/tools/mop-ups.htm.
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