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Congestive heart failure in the elderly
F Rengo1, D Acanfora, L Trojano
1Institute of Internal Medicine, Cardiology and Cardiovascular Surgery, Federico II University, School of Medicine, Via S. Pansini, 5-80131 Naples, Italy.
Insights
Congestive heart failure (CHF) incidence increases significantly with age, particularly in those over 75. Geriatric patients require tailored drug choices and dosages for effective CHF management due to unique age-related factors.
Area of Science:
- Geriatric Medicine
- Cardiology
- Internal Medicine
Background:
- Congestive heart failure (CHF) presents unique challenges in elderly populations.
- Physiological aging processes share similarities with CHF pathophysiology.
- Elderly patients often exhibit comorbidities and atypical presentations, complicating diagnosis and treatment.
Purpose of the Study:
- To review the epidemiology and specific considerations for congestive heart failure in the elderly.
- To highlight the impact of age-related physiological changes on CHF.
- To emphasize the need for tailored pharmacologic and multidisciplinary approaches in geriatric CHF management.
Main Methods:
- Literature review of international findings on CHF in the elderly.
- Analysis of population-based study data on elderly subjects.
- Discussion of age-related anatomical, functional, hormonal, and autonomic nervous system changes.
Main Results:
- CHF incidence and prevalence rise sharply in individuals aged 75 and older.
- Age-related changes can exacerbate CHF, leading to more severe disease progression.
- Elderly patients face increased risks from comorbidities, atypical symptoms, and iatrogenesis.
Conclusions:
- CHF treatment in the elderly necessitates careful drug selection and dosage adjustments to minimize side effects.
- A multidimensional approach, addressing comorbidities and functional status, is crucial for geriatric CHF patients.
- Further research into age- and disease-related changes is vital for developing effective 'successful aging' strategies.
Abstract:
Several aspects of congestive heart failure are discussed in the light of international literature and of recent findings of our group. The annual incidence of heart failure in elderly subjects, aged >or=75y, is 13 to 50/1000, while it is 1.6/1000 in people aged 45-54 y. The prevalence of heart failure is about 3% in subjects aged 45-64% in subjects aged more than 65 y and 10% in subjects aged more than 75 y. These data are confirmed by our population based study in elderly subjects. The etiology of congestive heart failure is similar in elderly and middle-aged patients. However, several anatomo-functional, hormonal and autonomic nervous system changes, typical of congestive heart failure, occur during physiologic ageing processes also. These findings may explain the dramatic evolution of congestive heart failure in elderly patients. Moreover, some features of the elderly - e.g. comorbidity, atypical clinical presentations, loss of autonomy, increased iatrogen risk should be considered. No specific drugs exist for the pharmacologic treatment of heart failure in the elderly, so that the geriatric specificity in the treatment of heart failure can be recognized in the art of drug choice and dosage, to obtain the best results with the least side effects. The multiple etiology of congestive heart failure, the comorbidity, the loss of autonomy and the deterioration of cognitive functions suggest the need for multidimensional approach and continuative intervention in elderly patients with heart disease, and in particular with congestive heart failure. Further studies on disease- and age-related changes are necessary to develop new and more potent strategies to secure 'successful ageing'.
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