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Related Experiment Videos

Recent genetic transfer between Lactococcus lactis and enterobacteria.

Alexander Bolotin1, Benoit Quinquis, Alexei Sorokin

  • 1Génétique Microbienne, Institut National de la Recherche Agronomique, Jouy en Josas, France. bolotine@jouy.inra.fr

Journal of Bacteriology
|September 18, 2004
PubMed
Summary
This summary is machine-generated.

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Lactococcus lactis likely donated the ycdB gene to enterobacteria through recent horizontal gene transfer. This gene transfer, observed between L. lactis subspecies, suggests potential mobilization via conjugation.

Area of Science:

  • Microbiology
  • Genomics
  • Bacterial Genetics

Background:

  • The genome of Lactococcus lactis shows recent gene exchange with enterobacteria.
  • The ycdB gene is implicated in this inter-bacterial genetic exchange.

Purpose of the Study:

  • To investigate the evolutionary history and transfer mechanisms of the ycdB gene.
  • To determine the directionality of gene transfer between lactococci and enterobacteria.

Main Methods:

  • Comparative analysis of ycdB orthologs across bacterial species.
  • Examination of ycdB gene distribution within Lactococcus lactis subspecies.
  • Inference of gene transfer events based on sequence data.

Main Results:

  • Evidence suggests Lactococcus lactis was the donor of the ycdB gene.

Related Experiment Videos

  • Three instances of ycdB gene transfer from lactococci to enterobacteria were identified.
  • The ycdB gene is transferable between Lactococcus lactis subspecies, likely via conjugation.

    • Conclusions:

    • The ycdB gene has undergone recent horizontal gene transfer from lactococci to enterobacteria.
    • Lactococcus lactis plays a role as a gene donor in bacterial evolution.
    • Conjugation is a plausible mechanism for ycdB mobilization between L. lactis subspecies.