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GENEVESTIGATOR. Arabidopsis microarray database and analysis toolbox.

Philip Zimmermann1, Matthias Hirsch-Hoffmann, Lars Hennig

  • 1Institute of Plant Sciences, Swiss Federal Institute of Technology and Zurich-Basel Plant Science Center, ETH Center, CH-8092 Zurich, Switzerland.

Plant Physiology
|September 18, 2004
PubMed
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GENEVESTIGATOR provides a web-browser interface for mining large microarray gene expression databases. This tool aids plant biologists in gene functional discovery by analyzing expression patterns across various conditions.

Area of Science:

  • Plant Biology
  • Bioinformatics
  • Genomics

Background:

  • High-throughput gene expression analysis is crucial in modern biology.
  • Limited user-friendly software exists for querying large microarray gene expression databases via web browsers.

Purpose of the Study:

  • To introduce GENEVESTIGATOR, a novel database and web-browser interface for mining Affymetrix GeneChip data.
  • To facilitate gene functional discovery and experimental design for plant biologists.

Main Methods:

  • Development of a database for Affymetrix GeneChip data.
  • Implementation of a web-browser interface for data mining.
  • Inclusion of tools to query gene expression patterns and identify specifically expressed genes.

Main Results:

Related Experiment Videos

  • GENEVESTIGATOR allows querying expression patterns of over 22,000 Arabidopsis genes across environmental conditions, growth stages, and organs.
  • Mining tools enable identification of genes expressed under specific stresses or in particular organs.
  • Expression profiles for 10,600 uncharacterized Arabidopsis genes are accessible.

Conclusions:

  • GENEVESTIGATOR serves as a valuable community resource for plant biologists.
  • The software provides contextual expression information to guide functional genomics research.
  • It supports the design of new experiments by revealing gene expression insights.