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Related Experiment Videos

Lens opacity: a population study.

R De Natale1, J Flammer

  • 1University Eye Clinic, Basel, Switzerland.

International Ophthalmology
|January 1, 1992
PubMed
Summary
This summary is machine-generated.

Normal lens opacity values increase significantly with age, as measured by the Opacity Lens Meter (OLM). This study establishes age-corrected OLM values for healthy individuals, showing a clear quadratic relationship between opacity and age.

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Area of Science:

  • Ophthalmology
  • Gerontology
  • Biomedical Engineering

Background:

  • Lens opacity is a key indicator of ocular aging and cataract development.
  • Establishing normative data is crucial for accurate clinical assessment and research.

Purpose of the Study:

  • To establish age-corrected normal values for the Opacity Lens Meter (OLM) 701.
  • To investigate the relationship between age and lens opacity in a healthy population.

Main Methods:

  • Measured 1598 eyes from 799 healthy volunteers using the Opacity Lens Meter (OLM) 701.
  • Analyzed the correlation between age and OLM readings.
  • Determined the best-fit function for opacity versus age.

Main Results:

Related Experiment Videos

  • A significant age-related increase in normal Opacity Lens Meter (OLM) values was observed.
  • Average OLM readings increased from approximately 10 units at age 30 to 20 units at age 65.
  • The relationship between lens opacity and age followed a quadratic function.
  • Interindividual variation in OLM readings was higher in older individuals.
  • High correlation (R = 0.93) was found between contralateral eyes.

    • Conclusions:

    • Normal lens opacity, as measured by the OLM, demonstrates a distinct age-dependent progression.
    • The established age-corrected values provide a valuable reference for clinical and research applications in ophthalmology.
    • The quadratic relationship highlights the non-linear increase in lens opacity with aging.