Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Hepatitis C virus and lichen planus.

Yumiko Nagao¹, Michio Sata

¹Research Center for Innovative Cancer Therapy, Kurume University School of Medicine, Kurume, Fukuoka, Japan.

Journal of Gastroenterology and Hepatology

|September 21, 2004

Summary

Hepatitis C virus (HCV) causes liver disease and cancer. This review examines lichen planus, a common HCV-related skin condition, and its treatment with interferon therapy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Improvements in Oral Lichen Planus Following Periodontal Treatment in a Patient With Metabolic Dysfunction-Associated Steatotic Liver Disease: A Case Report.

Cureus·2024

Same author

Survey of Medical Referral by Japanese Dentists for Patients With Hepatitis B, Hepatitis C, and Lichen Planus.

Cureus·2024

Same author

Hepatitis B and C infections among Japanese dental health workers: Insights from vaccination rates and screening results in the Oita prefecture.

Clinical and experimental dental research·2024

Same author

Onset of Oral Lichen Planus Led to Direct-Acting Antiviral Therapy in a Patient with Long-Term Hepatitis C: The Role of a Dentist as Gatekeeper.

Case reports in gastroenterology·2023

Same author

Education and Awareness Activities Regarding Hepatitis B and C Among Japanese Dental Health Workers in the Oita Prefecture.

Cureus·2022

Same author

Effects of Hepatitis C Virus Elimination by Direct-Acting Antiviral Agents on the Occurrence of Oral Lichen Planus and Periodontal Pathogen Load: A Preliminary Report.

International journal of dentistry·2021

Area of Science:

Hepatology
Virology
Dermatology

Background:

Hepatitis C virus (HCV) is a significant cause of chronic liver disease and hepatocellular carcinoma.
HCV is increasingly recognized for inducing various extrahepatic manifestations, including skin conditions like lichen planus.
The mechanisms underlying these extrahepatic manifestations are not fully understood but are often responsive to antiviral therapies.

Purpose of the Study:

This review focuses on lichen planus as a major extrahepatic manifestation of Hepatitis C virus infection.
To discuss the clinical presentation and management of HCV-related lichen planus.
To highlight the importance of recognizing and treating extrahepatic manifestations in HCV patients.

Main Methods:

Review of existing literature on Hepatitis C virus and its extrahepatic manifestations.
Focus on studies detailing lichen planus in the context of HCV infection.
Analysis of treatment outcomes, particularly interferon-based therapies.

Main Results:

Hepatitis C virus infection is associated with several extrahepatic conditions, including lichen planus.
Interferon (IFN) therapy, alone or with ribavirin, has shown efficacy in managing these extrahepatic lesions.
Lichen planus, though often overlooked, represents a significant extrahepatic manifestation of HCV.

Conclusions:

Lichen planus is a notable extrahepatic manifestation of Hepatitis C virus infection.
Interferon-based treatments can effectively alleviate or resolve HCV-induced lichen planus.
Increased awareness and management of extrahepatic manifestations are crucial in comprehensive HCV care.

Related Experiment Videos