Related Experiment Video
Updated: Aug 22, 2026

Characteristics of Precipitation-formed Polyethylene Glycol Microgels Are Controlled by Molecular Weight of Reactants
Published on: December 23, 2013
Ethylene glycol toxicity
Robert D Cox1, William J Phillips
1Emergency Medicine, Mississippi Regional Poison Control Center, University of Mississippi Medical Center, Jackson, MS 39216, USA.
Abstract:
Ethylene glycol is an inexpensive, readily available substance that may be associated with accidental or intentional toxicity. Toxicity from this substance may be encountered in the military and civilian populations. Because it is highly toxic and can result in death if not treated appropriately, it is imperative to recognize the signs and symptoms of intoxication. Two cases are presented and the diagnosis and treatment of ethylene glycol toxicity are discussed. Fomepizole, a new medication for ethylene glycol toxicity, has changed the management of this poisoning. It increases the elimination half-life of ethylene glycol, thus delaying the formation of toxic metabolites.
Related Concept Videos
Toxic Reactions: Overview
Toxicity falls into two primary categories: local and systemic.
Local toxicity appears at the exposure site, such as protein denaturation caused by caustic substances.
In contrast, systemic toxicity requires the toxic agent's absorption and distribution,...
Hepatic Encephalopathy
Drug Toxicity: Dose-Dependent Reactions
Hyperosmolar Hyperglycemic State
Cytotoxic Edema: Pathophysiology
Drug Toxicity: Overview
