Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

iPS Cell Differentiation01:22

iPS Cell Differentiation

3.0K
The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.
3.0K
Induced Pluripotent Stem Cells01:06

Induced Pluripotent Stem Cells

5.3K
Stem cells are undifferentiated cells that divide and produce different cell types. Ordinarily, cells that have differentiated into a specific cell type are terminally differentiated; however, scientists have found a way to reprogram these mature cells so that they dedifferentiate and return to an unspecialized, proliferative state. These cells are pluripotent like embryonic stem cells—able to produce all cell types—and are called induced pluripotent stem cells (iPSCs).
Somatic...
5.3K
Stem Cell Culture01:17

Stem Cell Culture

6.0K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
6.0K
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

3.8K
The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
3.8K
EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

3.3K
Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
3.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Combustion Synthesis and Photoluminescence Properties of Dy<sup>3+</sup>Activated Li₂Sr.₂Al₂PO₄F₉ Phosphor for Solid-State Lighting Applications.

Luminescence : the journal of biological and chemical luminescence·2025
Same author

Effect of Dopant Concentration on Luminescence Properties of Na<sub>3</sub>Ca<sub>2</sub>(SO<sub>4</sub>)<sub>3</sub>F: RE (RE = Eu<sup>3+</sup>, Dy<sup>3+</sup>) Phosphor for Solid-State Lighting.

Luminescence : the journal of biological and chemical luminescence·2024
Same author

Thermoluminescence study of CaNa<sub>2</sub> (SO<sub>4</sub> )<sub>2</sub> phosphor doped with Eu<sup>3+</sup> and synthesized by combustion method.

Luminescence : the journal of biological and chemical luminescence·2020
Same author

Beam Energy and Centrality Dependence of Direct-Photon Emission from Ultrarelativistic Heavy-Ion Collisions.

Physical review letters·2019
Same author

FIBROADENOMA OF ABERRANT BREAST TISSUE IN THE VULVA.

Medical journal, Armed Forces India·2017
Same author

A tumor deconstruction platform identifies definitive end points in the evaluation of drug responses.

Oncogene·2015

Related Experiment Video

Updated: Jan 7, 2026

Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
10:30

Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Published on: August 4, 2022

3.4K

Stem cell pharmacogenomics.

S A Bapat1, G C Mishra

  • 1National Centre for Cell Science, NCCS Complex, Ganeshkhind, Pune 411 007, Maharashtra, India. sabapat@nccs.res.in

Current Topics in Medicinal Chemistry
|September 24, 2004
PubMed
Summary
This summary is machine-generated.

Stem cell pharmacogenomics (SCP) merges stem cell therapy and pharmacogenomics for personalized treatments. This field requires advancements in genomics and bioinformatics to improve stem cell medicine and human quality of life.

More Related Videos

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
12:40

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery

Published on: May 19, 2018

10.6K
A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening
07:18

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

Published on: May 12, 2017

6.8K

Related Experiment Videos

Last Updated: Jan 7, 2026

Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
10:30

Technical Applications of Microelectrode Array and Patch Clamp Recordings on Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes

Published on: August 4, 2022

3.4K
Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
12:40

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery

Published on: May 19, 2018

10.6K
A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening
07:18

A Simple Method to Identify Kinases That Regulate Embryonic Stem Cell Pluripotency by High-throughput Inhibitor Screening

Published on: May 12, 2017

6.8K

Area of Science:

  • Regenerative Medicine
  • Genomics
  • Bioinformatics

Background:

  • Therapeutic stem cell applications offer novel treatments for genetic and degenerative diseases.
  • Pharmacogenomics enables individualized treatment strategies for diverse medical conditions.

Purpose of the Study:

  • To introduce stem cell pharmacogenomics (SCP) as a new research niche.
  • To discuss priority issues in advancing SCP based on current principles.

Main Methods:

  • Integration of genomics, proteomics, and bioinformatics technologies.
  • Application of existing principles from pharmacogenomics, stem cell biology, and transplantation medicine.

Main Results:

  • Identification of stem cell pharmacogenomics as a promising interdisciplinary field.
  • Highlighting key areas for research and development in SCP.

Conclusions:

  • Stem cell pharmacogenomics holds potential for optimizing stem cell therapies.
  • Advancements in SCP are crucial for improving human health and quality of life through regenerative medicine.