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Updated: Aug 18, 2026

Assay for Neural Induction in the Chick Embryo
11:14

Assay for Neural Induction in the Chick Embryo

Published on: February 13, 2009

Cannabinoid receptor, CB1, expression follows neuronal differentiation in the early chick embryo

Jo Begbie1, Patrick Doherty, Anthony Graham

  • 1Molecular Neurobiology Group, MRC Centre for Developmental Neurobiology, Kings College London, UK.

Journal of Anatomy
|September 24, 2004
PubMed

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Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...