Septic shock after transrectal ultrasound guided prostate biopsy. Is ciprofloxacin prophylaxis always protecting?

Saleh Binsaleh1, Mana Al-Assiri, Samuel Aronson

  • 1Division of Urology, Montreal General Hospital, McGill University Health Center, Montreal, Quebec, Canada.

Insights

Septic shock occurred after a prostate biopsy, even with antibiotic prophylaxis. Recent antibiotic use may have contributed to treatment failure in this case.

Area of Science:

  • Urology
  • Infectious Diseases
  • Medical Case Reports

Background:

  • Transrectal ultrasound-guided prostate biopsy is a common procedure for diagnosing prostate cancer.
  • Antibiotic prophylaxis is standard to prevent infectious complications.
  • Recent antibiotic exposure can influence treatment efficacy and infection risk.

Observation:

  • A patient developed septic shock following a prostate biopsy.
  • The patient had received ciprofloxacin prophylaxis before the biopsy.
  • The patient had a recent history of treatment with ciprofloxacin for other infections.

Findings:

  • Despite ciprofloxacin prophylaxis, the patient experienced a severe infection (septic shock).
  • This suggests potential antibiotic resistance or altered susceptibility due to recent prior antibiotic exposure.
  • The case highlights a rare but serious complication of prostate biopsy.

Implications:

  • Clinicians should consider recent antibiotic history when prescribing prophylaxis for prostate biopsies.
  • Further research may be needed to optimize prophylactic strategies in patients with recent antibiotic exposure.
  • This case underscores the importance of vigilance for infectious complications post-procedural.

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