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Nuclear factor-kappaB: the enemy within

Bharat B Aggarwal1

  • 1Cytokine Research Laboratory, Department of Experimental Therapeutics, Unit 143, The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. aggarwal@mdanderson.org

Cancer Cell
|September 24, 2004
PubMed
Summary

Nuclear factor NF-kappaB (NF-kappaB), a key inflammatory regulator, drives cancer development and progression. Inhibiting NF-kappaB activation offers a promising strategy for cancer prevention and treatment.

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