Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Surgical treatment for epilepsy.

Gregory D Cascino1

  • 1Mayo Clinic and Mayo Foundation, Department of Neurology, Division of Epilepsy, 200 First Street, SW, Rochester, MN 55905, USA. gcascino@mayo.edu

Epilepsy Research
|September 24, 2004
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mood and Anxiety Disorders and Suicidality in Patients With Newly Diagnosed Focal Epilepsy: An Analysis of a Complex Comorbidity.

Neurology·2025
Same author

Focal to bilateral tonic-clonic seizures in newly diagnosed focal epilepsy.

Epilepsia·2025
Same author

Drug-resistant temporal lobe epilepsy with temporal encephaloceles: How far to resect.

Epilepsy & behavior : E&B·2023
Same author

Functional neurological seizures and migraine: A systematic review and case series.

Epilepsy & behavior : E&B·2023
Same author

Seizure control in women with epilepsy undergoing assisted reproductive technology.

Epilepsia·2023
Same author

Later onset focal epilepsy with roots in childhood: Evidence from early learning difficulty and brain volumes in the Human Epilepsy Project.

Epilepsia·2023

Early epilepsy surgery can significantly improve outcomes for patients with medically refractory epilepsy. Identifying suitable candidates early leads to seizure freedom and enhanced quality of life.

Area of Science:

  • Neurology
  • Neurosurgery
  • Epileptology

Background:

  • A significant portion of epilepsy patients develop drug-resistant seizures.
  • Intractable epilepsy leads to progressive medical, physical, and social disability.

Purpose of the Study:

  • To review the efficacy of early epilepsy surgery for intractable partial epilepsy.
  • To support the identification of early surgical candidates.

Main Methods:

  • Review of literature supporting early surgical intervention.
  • Analysis of factors identifying favorable surgical candidates.
  • Comparison of surgical outcomes with antiepileptic drug therapy.

Main Results:

  • Early epilepsy surgery can achieve seizure freedom in selected patients.

Related Experiment Videos

  • Surgical intervention improves quality of life and social participation.
  • Medial temporal lobe epilepsy and lesional pathology are favorable indicators for surgery.

    • Conclusions:

    • Epilepsy surgery is a favorable treatment option compared to antiepileptic drugs for intractable partial epilepsy.
    • Early presurgical evaluation is crucial for patients unresponsive to initial drug therapy.
    • Ictal semiology, MRI, and electroclinical correlation aid in identifying surgical candidates.