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Updated: Aug 22, 2026
Transient Expression in Nicotiana Benthamiana Leaves for Triterpene Production at a Preparative Scale
Published on: August 16, 2018
Tetracyclic triterpenoids from the leaves of Azadirachta indica
Bina S Siddiqui1, Farhana Afshan, Tahsin Gulzar
1International Center for Chemical Sciences, H.E.J. Research Institute of Chemistry, University of Karachi, Karachi, 75270, Pakistan. bina@khi.comsats.net.pk
Abstract:
Two new tetracyclic triterpenoids zafaral [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-methoxy-7alpha-acetoxy-1,14-dien-3,16-dione-21-al] (1) and meliacinanhydride [24,25,26,27-tetranorapotirucalla-(apoeupha)-6alpha-hydroxy,11alpha-methoxy-7alpha,12alpha-diacetoxy,1,14,20(22)-trien-3-one] (2) have been isolated from the methanolic extract of neem leaves along with two known constituents nimocinol and isomeldenin. Their structures and the relative configurations were determined by spectroscopic methods ((1)H and (13)C NMR, IR, and MS) and 2D NMR experiments.
