Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Experimental facial augmentation with hydroxyapatite cement.

Mimi S Kokoska¹, Craig D Friedman, Richard D Castellano

¹Central Arkansas Veterans Healthcare System and the University of Arkansas for Medical Sciences, Little Rock, AR, USA.

Archives of Facial Plastic Surgery

|September 24, 2004

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Extreme Lateral Infracondylar Approach for Occipital Artery to Vertebral Artery (V3) Bypass for Vertebrobasilar Insufficiency: 2-Dimensional Operative Video.

Operative neurosurgery (Hagerstown, Md.)·2025

Same author

Anatomical determinants of occipitocervical fusion in skull base chordoma resection: a systematic review of the literature with illustrative cases.

Neurosurgical focus·2024

Same author

Safety and efficacy of sphenopalatine ganglion stimulation for chronic cluster headache: a double-blind, randomised controlled trial.

The Lancet. Neurology·2019

Same author

Erratum: The Laparoscopically Harvested Omental Free Flap: A Compelling Option for Craniofacial and Cranial Base Reconstruction.

Journal of neurological surgery. Part B, Skull base·2018

Same author

Reprocessing Standards for Medical Devices and Equipment in Otolaryngology: Safe Practices for Scopes, Speculums, and Single-Use Devices.

Otolaryngologic clinics of North America·2018

Same author

Neuroradiological and Neuropathological Changes After 177Lu-Octreotate Peptide Receptor Radionuclide Therapy of Refractory Esthesioneuroblastoma.

Operative neurosurgery (Hagerstown, Md.)·2018

Preformed hydroxyapatite (HA) implants and HA cement show promise for craniofacial augmentation in rabbits. These materials, used alone or together, were well-tolerated and integrated without adverse reactions.

Area of Science:

Biomaterials Science
Craniofacial Surgery
Regenerative Medicine

Background:

Hydroxyapatite (HA) is a bioceramic material widely used in bone reconstruction.
Onlay augmentation is a surgical technique to enhance facial contours.

Purpose of the Study:

To evaluate the efficacy and biocompatibility of preformed HA disks and HA cement for onlay augmentation in a rabbit model.

Main Methods:

Prospective study in 16 rabbits.
Implantation of HA disks and HA cement on nasal dorsum and supraorbital bone.
Gross and histologic examination at 3-24 months.

Main Results:

No infections, adverse reactions, or extrusion observed.
HA disks maintained dimensions; HA cement showed a 15% decrease in dimensions.

Related Experiment Videos

Implants were enclosed in vascularized fibrous capsules; HA cement demonstrated osteoconversion and osteointegration.

Conclusions:

Preformed HA implants and HA cement are safe and effective for augmenting non-stress-bearing craniofacial areas.
Combination of HA disks and HA cement promotes osteoconversion in the cement layer.
Further research may explore long-term stability and clinical applications.