Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Chronic hepatitis C virus infection].

M Iñarrairaegui1, I Elizalde, A Martínez Echeverría

  • 1Servicio de Aparato Digestivo, Hospital de Navarra, 31008 Pamplona, Spain. pitudoc@yahoo.es

Anales Del Sistema Sanitario De Navarra
|September 24, 2004
PubMed
Summary

Chronic hepatitis C virus (HCV) infection can lead to serious liver damage and extrahepatic manifestations. Diagnosis involves serological and virological tests, with ongoing debate about liver biopsy for patients with normal transaminases.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Monitoring endoscopic postoperative recurrence in Crohn's disease after an ileocecal resection. Does capsule endoscopy have a role in the short and long term?

Acta gastro-enterologica Belgica·2022
Same author

[Effectiveness of second-generation direct-acting antivirals in chronic hepatitis C].

Anales del sistema sanitario de Navarra·2017
Same author

[Relation between preoperative prognostic Onodera's Index and postsurgery complications in the R0 gastric carcinoma resection].

Anales del sistema sanitario de Navarra·2017
Same author

[Hepatocellular carcinoma].

Anales del sistema sanitario de Navarra·2016
Same author

[Predictive pre-treatment value of the Prognostic Nutritional Index on survival in gastric carcinoma].

Anales del sistema sanitario de Navarra·2016
Same author

[Radioembolization with (90)Y-microspheres for liver tumors].

Revista espanola de medicina nuclear e imagen molecular·2015

Area of Science:

  • Hepatology
  • Virology
  • Immunology

Context:

  • Hepatitis C virus (HCV) infection frequently leads to chronic disease.
  • A significant portion of patients develop extrahepatic manifestations due to HCV's lymphotropism.
  • Unspecific symptoms and normal transaminase levels in one-third of patients complicate diagnosis.

Purpose:

  • To summarize the clinical presentation, diagnosis, and management considerations for chronic hepatitis C virus (HCV) infection.
  • To highlight the diagnostic challenges posed by variable transaminase levels and extrahepatic manifestations.
  • To discuss the role of liver biopsy in staging fibrosis and inflammation for treatment decisions.

Summary:

  • Chronic hepatitis C virus (HCV) infection is characterized by persistent viral presence, potential extrahepatic manifestations like mixed cryoglobulinemia and autoantibody production, and variable transaminase levels.

Related Experiment Videos

  • Diagnosis relies on detecting HCV antibodies and RNA, confirming active infection.
  • Assessing liver fibrosis and inflammation post-diagnosis is crucial for prognosis and treatment planning, with liver biopsy being the current standard, though its use in patients with normal transaminases remains debated.

    • Impact:

    • Improved understanding of chronic HCV presentation and diagnostic nuances.
    • Informs clinical decision-making regarding further investigations, particularly liver biopsy.
    • Contributes to better patient management strategies for chronic hepatitis C.