[Rhombencephalitis caused by Listeria: clinical-radiological correlation]

N Aymerich1, F Lacruz, J Gállego

  • 1Servicio de Neurología, Hospital de Navarra, Pamplona.

Insights

Rhombencephalitis, a rare brainstem infection, presents in two phases. Early recognition of symptoms and prompt MRI are crucial for effective antibiotic treatment and improved patient outcomes.

Area of Science:

  • Neurology
  • Infectious Diseases

Background:

  • Rhombencephalitis is an infrequent yet serious brainstem infection.
  • It primarily affects previously healthy individuals.

Observation:

  • The case details a patient initially presenting with nonspecific symptoms like headache, nausea, and fever.
  • This progressed to focal neurological deficits, including cranial nerve asymmetry, cerebellar signs, and sensory deficits.
  • Complications included acute respiratory insufficiency and urinary retention.

Findings:

  • Early magnetic resonance imaging (MRI) revealed characteristic hyperintense lesions in the brainstem (bulb and pons) on T2 sequences.
  • Initial treatment with ampicillin and tobramycin was modified to vancomycin due to Listeria monocytogenes (serotype 4B) resistance to ampicillin.
  • The patient survived but experienced residual oculomotor and micturition issues.

Implications:

  • Emphasizes the critical role of early clinical recognition of rhombencephalitis signs.
  • Highlights the importance of prompt MRI for diagnosis and guiding appropriate antibiotic therapy.
  • Underscores the need for timely intervention to improve prognosis and minimize sequelae.

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