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Updated: Aug 22, 2026
Comparing Metastatic Clear Cell Renal Cell Carcinoma Model Established in Mouse Kidney and on Chicken Chorioallantoic Membrane
Published on: February 8, 2020
[Renal cell carcinoma with late lung and ocular metastases]
Oscar Rodríguez Faba1, Francisco Martínez Gómez, Luis Parra Muntaner
1Servicio de Urologia, Hospital Central de Asturias, Oviedo, Asturias, España. oscar.rodriguez@sespa.princast.es
Objectives:
We report one case of ocular and lung metastases seven years after radical nephrectomy for renal cell carcinoma.
Methods:
The case of a 45-year-old male patient who underwent radical nephrectomy for a localized renal cell carcinoma (T2N0M0) in 1995 was found in a review of malignant renal neoplastic pathology.
Results:
Seven years later he presented with a lung metastasis requiring neumonectomy, and an ocular metastasis requiring enucleation. He is currently receiving systemic treatment with interferon and interleukin.
Conclusions:
Clinical presentation and evolution of metastasic renal carcinoma is very variable, a difference with other neoplasias. Ocular localization is exceptional and may appear long time after primary tumor; clinically, it may be asymptomatic or present with sudden sight loss. MRI, CT scan and retinal examination are the diagnostic methods employed, and treatment may be surgery, brachytherapy or radiotherapy depending on location and size of the lesion.
