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A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
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Aptamer-functionalized Au nanoparticles for the amplified optical detection of thrombin

Valeri Pavlov1, Yi Xiao, Bella Shlyahovsky

  • 1Institute of Chemistry, The Farkas Center for Light-Induced Processes, The Hebrew University of Jerusalem, Jerusalem 91904, Israel.

Journal of the American Chemical Society
|September 24, 2004
PubMed

Abstract:

The catalytic enlargement of aptamer-functionalized Au nanoparticles amplifies the optical detection of aptamer-thrombin complexes in solution and on surfaces.

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