Related Experiment Video

Updated: Aug 22, 2026

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
09:36

Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers

Published on: July 28, 2022

Infant colic and feeding difficulties

C Miller-Loncar1, R Bigsby, P High

  • 1Brown Medical School, Department of Pediatrics, Infant Development Center, Women and Infants Hospital of Rhode Island & E. P. Bradley Hospital, Providence, RI 02905, USA. cynthia_loncar@brown.edu

Archives of Disease in Childhood
|September 24, 2004
PubMed

Insights

Infants with colic often experience feeding difficulties and gastro-oesophageal reflux (GOR), impacting infant regulation and increasing parental stress. These feeding issues may indicate ongoing regulatory problems in colicky infants.

Area of Science:

  • Pediatric Health
  • Infant Development
  • Clinical Psychology

Background:

  • Colic is a common condition in infants, often associated with excessive crying.
  • Feeding difficulties and gastro-oesophageal reflux (GOR) are frequently reported in infants but their specific relationship with colic requires further investigation.

Purpose of the Study:

  • To investigate the association between colic and feeding difficulties in infants.
  • To examine the impact of these feeding challenges on parental functioning.
  • To explore the prevalence of gastro-oesophageal reflux (GOR) in infants with colic.

Main Methods:

  • A cohort of 43 infants (6-8 weeks old) were divided into colic (n=19) and comparison (n=24) groups.
  • Assessments included infant oral motor skills, mother-infant feeding interactions, maternal questionnaires, and abdominal ultrasound for GOR.
  • Data were collected across two study visits.

Main Results:

  • Infants in the colic group exhibited more disorganized feeding behaviors, less rhythmic sucking, and increased discomfort post-feeding.
  • Colic group infants showed higher incidence of GOR via ultrasound and maternal report.
  • Mothers of infants in the colic group reported significantly higher levels of parenting stress.

Conclusions:

  • This study provides initial evidence linking feeding problems to a subgroup of infants diagnosed with colic.
  • The findings highlight the detrimental effects of feeding difficulties on both infant and parental well-being.
  • The observed association suggests that feeding and regulatory issues may be interconnected in infants with significant colic symptoms.
Abstract

More Related Videos

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling07:11

Assessment of the Efficacy of An Osteopathic Treatment in Infants with Biomechanical Impairments to Suckling

Published on: February 5, 2019

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System06:19

Non-Nutritive Suck Parameters Measurements Using a Custom Pressure Transducer System

Published on: April 19, 2024

Related Concept Videos

Pyloric Obstruction01:11

Pyloric Obstruction

Pyloric obstruction, also referred to as gastric outlet obstruction, is a condition characterized by narrowing or blockage at the pylorus—the muscular valve regulating the flow of stomach contents into the duodenum. When this passage becomes impaired, the stomach cannot effectively empty its contents into the small intestine. This disruption leads to a range of gastrointestinal symptoms, including early satiety, bloating, epigastric pain, postprandial nausea, persistent vomiting, and...
Intestinal Obstruction II: Pathophysiology01:07

Intestinal Obstruction II: Pathophysiology

Intestinal obstruction triggers a series of physiological responses, starting with gas and fluid accumulation in the bowel segment proximal to the obstruction, leading to distension. This distended intestine compresses the diaphragm, hindering lung expansion and potentially leading to reduced respiratory effort, atelectasis, and pneumonia.To overcome the blockage, the gut intensifies contractions, causing colicky abdominal pain, nausea, and vomiting, which reduces fluid and food intake and...
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Assessment of the Rectum and Anus01:25

Assessment of the Rectum and Anus

Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy01:30

Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy

Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the colonic...