Continuous-flow peritoneal dialysis: update

The theoretical constructs of and limited clinical experiments with, continuous flow peritoneal dialysis (CFPD) are very promising. Specifically, removal of small molecular solutes has been shown to approximate that with quotidian hemodialysis. However progress has been slow because of the lack of an adequate peritoneal access device and the high cost of peritoneal dialysis (PD) solution generation. Several novel designs for CFPD catheters have been introduced during the past year. Those designs may solve some of the problems of fluid mixing and recirculation. This review of the past and latest developments in CFPD identifies the factors that limit the widespread use of this promising therapy.