Early intravenous cannulation in children during sevoflurane induction

Donald Schwartz1, Neil Roy Connelly, Srinivasa Gutta

  • 1Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA.

Paediatric Anaesthesia
|September 24, 2004
PubMed

Insights

For pediatric patients undergoing sevoflurane anesthesia, attempting intravenous line placement 30 seconds after loss of lid reflex increases movement and laryngospasm risk. Waiting 120 seconds is recommended for safer intravenous access.

Area of Science:

  • Pediatric Anesthesiology
  • Patient Safety in Surgery

Background:

  • Previous studies indicated early intravenous line placement was safe in children under halothane anesthesia.
  • The safety of early intravenous line placement with sevoflurane anesthesia in pediatric patients remained unknown.

Purpose of the Study:

  • To determine if early (30 seconds) versus late (120 seconds) intravenous line placement after loss of lid reflex impacts safety during sevoflurane inhalation induction in children.

Main Methods:

  • Pediatric patients aged 1-18 years undergoing elective general anesthesia were randomized.
  • Intravenous line placement was attempted either 30 or 120 seconds post-loss of lid reflex.
  • Movement, laryngospasm incidence, and difficulty of intravenous placement were recorded.

Main Results:

  • Significantly more movement occurred during intravenous placement in the early group (30s) compared to the late group (120s).
  • Laryngospasm occurred in eight patients in the early group versus none in the late group.
  • Older children in the early group experienced more significant movement.

Conclusions:

  • Attempting intravenous placement 30 seconds after loss of lid reflex during sevoflurane inhalation induction in children leads to increased movement and higher laryngospasm incidence.
  • A 120-second waiting period after loss of lid reflex is recommended before attempting intravenous placement in this pediatric population.
Abstract

Related Concept Videos

Endotracheal Intubation I: Procedure01:15

Endotracheal Intubation I: Procedure

Endotracheal or ET intubation is a critical medical procedure used to secure a patient's airway, often in acute respiratory distress, apnea, upper airway obstruction, ineffective clearance of secretions, high risk for aspiration, or during general anesthesia.
The ET tube comprises various components, including a standard adaptor to attach a bag-valve-mask (BVM) or ventilator, a cuff, a pilot balloon, and radiopaque markings along its length to measure the insertion distance. The tube sizes...
Parenteral Anesthetics: Overview01:24

Parenteral Anesthetics: Overview

Intravenous anesthetics are drugs administered parenterally to induce anesthesia or sedation. Propofol is a widely used agent formulated as a 1% emulsion in soybean oil, glycerol, and egg phosphatide. It induces rapid anesthesia primarily due to its rapid distribution from the bloodstream to target tissues and is metabolized in the liver. However, it can cause significant pain on injection and hypertriglyceridemia. Fospropofol, a water-based prodrug of propofol, lacks these adverse effects.
Drug Dosing: Infants and Children01:29

Drug Dosing: Infants and Children

Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
Endotracheal Intubation II: Nursing Management01:17

Endotracheal Intubation II: Nursing Management

Endotracheal intubation is a critical procedure that can be lifesaving for many patients with respiratory distress or failure. The role of nursing in managing endotracheal tubes is pivotal, as it involves pre-intubation preparation, assisting during the procedure, and post-extubation care.
1. Nursing Care of Patients Before Intubation
Before the endotracheal intubation procedure, nurses play an essential role in ensuring the process goes smoothly. The nurses must be familiar with intubation...
Inhalational Anesthetics: Overview01:20

Inhalational Anesthetics: Overview

Inhalation anesthetics are drugs that induce general anesthesia upon inhalation. They work by increasing the sensitivity of GABAA receptors or inhibiting NMDA receptors, leading to a decrease in central nervous system activity. The depth of anesthesia can be rapidly adjusted by changing the concentration of the inhaled gas. Some common examples of inhalational anesthetics include volatile liquids like isoflurane, desflurane, sevoflurane and gases like xenon and nitrous oxide. Isoflurane, a...
General Anesthesia: Overview01:24

General Anesthesia: Overview

Anesthesia is a medical procedure that uses drugs for CNS suppression to enable painless surgeries and procedures. The selection of anesthetics is influenced by their pharmacokinetic properties, side effects, and patient characteristics. Various types of anesthesia include general, local, regional, spinal, and inhalational.
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...